Choice ball: a response interface for two-choice psychometric discrimination in head-fixed mice
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چکیده
منابع مشابه
Innovative Methodology Choice ball: a response interface for two-choice psychometric discrimination in head-fixed mice
Sanders JI, Kepecs A. Choice ball: a response interface for twochoice psychometric discrimination in head-fixed mice. J Neurophysiol 108: 3416–3423, 2012. First published September 26, 2012; doi:10.1152/jn.00669.2012.—The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparati...
متن کاملChoice ball: a response interface for two-choice psychometric discrimination in head-fixed mice.
The mouse is an important model system for investigating the neural circuits mediating behavior. Because of advances in imaging and optogenetic methods, head-fixed mouse preparations provide an unparalleled opportunity to observe and control neural circuits. To investigate how neural circuits produce behavior, these methods need to be paired with equally well-controlled and monitored behavioral...
متن کاملBall : a response interface for two - choice psychometric 2 discrimination in head - fixed mice
24 The mouse is an important model system for investigating the neural circuits 25 mediating behavior. Due to advances in imaging and optogenetic methods, head26 fixed mouse preparations provide an unparalleled opportunity to observe and 27 control neural circuits. In order to investigate how neural circuits produce 28 behavior, these methods need to be paired with equally well-controlled and 2...
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Rats and mice receive a constant bilateral stream of tactile information with their large mystacial vibrissae when navigating in their environment. In a two-alternative forced choice paradigm (2-AFC), head-fixed rats and mice learned to discriminate vibrotactile frequencies applied simultaneously to individual whiskers on the left and right sides of the snout. Mice and rats discriminated 90-Hz ...
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Psychophysical tasks for non-human primates have been instrumental in studying circuits underlying perceptual decision-making. To obtain greater experimental flexibility, these tasks have subsequently been adapted for use in freely moving rodents. However, advances in functional imaging and genetic targeting of neuronal populations have made it critical to develop similar tasks for head-fixed m...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2012
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00669.2012